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Retinoid X Receptor beta antibody, Internal

Anti-Retinoid X Receptor beta antibody, Internal used in Western Blot (WB). GTX89670
Anti-Retinoid X Receptor beta antibody, Internal used in Western Blot (WB). GTX89670

Cat. No. GTX89670

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Retinoid X Receptor beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89670-PEP).

Product Note

This antibody is expected to recognise an epitope corresponding to aa 70-83 of human RXR beta protein and does not cross-react with either RXR alpha or gamma.

Predict Reactivity

Mouse, Rat, Bovine, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence CRDGMGDSGRDSRSP, from the internal region of the protein sequence according to NP_068811.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

RRID

AB_10725131

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

retinoid X receptor beta , DAUDI6 , H-2RIIBP , NR2B2 , RCoR-1

Cellular Localization

Nucleus

Background

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Database

Research Area

DATA IMAGES

Anti-Retinoid X Receptor beta antibody, Internal used in Western Blot (WB). GTX89670

GTX89670 WB Image

WB analysis of A431 lysate using GTX89670 Retinoid X Receptor beta antibody, Internal.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

Anti-Retinoid X Receptor beta antibody, Internal used in Western Blot (WB). GTX89670

GTX89670 WB Image

WB analysis of HEK293 overexpressing Retinoid X Receptor beta (mock transfection in first lane) using GTX89670 Retinoid X Receptor beta antibody, Internal.

REFERENCE

Application Reference

Ho TC et al. J Biol Chem 2011; 286 (41) : 35943-54 Pigment epithelium-derived factor (PEDF) promotes tumor cell death by inducing macrophage membrane tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399