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Retinoid X Receptor beta antibody

Cat. No. GTX79265

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP, ChIP assay, Gel supershift assays, IHC

Reactivity

 Human, Mouse, Bovine
Package
100 μl ($399)
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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1,000
IP Assay dependent
ChIP assay Assay dependent
Gel supershift assays Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Mouse

Immunogen

Synthetic peptide corresponding to residues Q(190) K S D Q G V E G P G A T(202) of mouse RXR beta.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11169592

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

retinoid X receptor beta , AL023085 , H-2RIIBP , Nr2b2 , RCoR-1 , Rub

Cellular Localization

Nucleus

Background

Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta, also known as RCoR-1, controls such a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR). The corresponding gene for the retinoid X receptor beta is NR2B2.

Database

Research Area

REFERENCE

Application Reference

Tang T et al. J Control Release 2019; 301 : 42-53 Tumor-specific macrophage targeting through recognition of retinoid X receptor beta.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399