GeneTex
United States (US)

Retinoid X Receptor gamma antibody

RXRG-antibody_IHC-P_GTX15518-1_18121411_925.jpg
RXRG-antibody-GTX15518-IHC-2_18121411_363.jpg

Cat No. GTX15518

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. WB: Use at a concentration of 1 - 2 μg/ml. Predicted molecular weight: 51 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

51 kDa. ( Note )

Positive Control

Breast carcinoma and prostate
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Mouse) (N terminal).

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Retinoid X Receptor Gamma,Nr2B3,Rxrg

Cellular Localization

Nuclear

Background

Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.

Database

Research Area

DATA IMAGES
RXRG-antibody_IHC-P_GTX15518-1_18121411_925.jpg

GTX15518 IHC-P Image

Human Prostate Carcinoma stained with anti-Retinoic X Receptor gamma antibody (GTX15518)

RXRG-antibody-GTX15518-IHC-2_18121411_363.jpg

GTX15518 IHC-P Image

GTX15518 staining Retinoid X Receptor gamma in breast carcinoma by Immunohistochemistry (FFPE-sections).

REFERENCE
Package List Price ($)
$ 319