GeneTex

  • Country / Location Selection

United States (US)

Rho GDI alpha antibody

Cat. No. GTX13062

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP

Reactivity

 Human, Mouse, Bovine
Package
50 μg ($399)
See all Rho GDI alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5-1.0 μg/ml
IP 4 μg
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Positive Control

HL-60, HeLa, Hs294T, Jurkat, NIH3T3, 3T3/A31

Product Note

The antibody recognizes Rho-GDI and cross-reacts with D4-GDI.

PROPERTIES

Form

Liquid

Buffer

0.1M Tris-Glycine buffer, 0.15M NaCl

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

~1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

GST fusion protein corresponding to full-length human Rho-GDI.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Rho GDP dissociation inhibitor alpha , GDIA1 , HEL-S-47e , NPHS8 , RHOGDI , RHOGDI-1

Cellular Localization

Cytoplasm

Background

GDP - Dissociation inhibitors (GDIs) modulate GTPase activity by binding to small G-proteins and regulating GDP/GTP exchange of inflammatory cell activity, including motility, formation of toxic oxygen metabolites and generation of proinflammatory cytokines. RhoGDI may also be critical for the cellular compartmentalization of GTPases. RhoGDI, which can bind to Rho, Rac, and cdc42, is localized in the cytosol. D4GDI, an abundant hematopoietic cell GDI for the Ras-related Rho family GTPases, is a substrate of the apoptosis protease.

Database

  • Gene ID: 396 ARHGDIA
  • UniProt: P52565 ARHGDIA

Research Area

REFERENCE

There are currently no references for Rho GDI alpha antibody (GTX13062). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Rho GDI alpha antibody (GTX13062). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399