RyR2 (phospho Ser2814) antibody

Cat. No. GTX00626

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human
Package	100 μl ($419)

See all RyR2 products

Datasheet
Document

View product citations for antibody GTX00626 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:2000
IHC-P	1:50-1:200
ELISA	Assay dependent

Not tested in other applications.

Calculated MW

565 kDa. ( Note )

Predict Reactivity

Rabbit, Sheep, Bovine, Horse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human RYR2 around the phosphorylation site of Ser2814.

Purification

Purified by sequential chromatography on phospho-peptide and non-phospho-peptide columns

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ryanodine receptor 2 , ARVC2 , ARVD2 , RYR-2 , RyR , VTSIP

Cellular Localization

Membrane

Background

This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]

Database

Gene ID: 6262 RYR2
UniProt: Q92736 RYR2

Research Area

DATA IMAGES

GTX00626 ELISA Image

ELISA analysis of RyR2 phospho- and non-phospho peptide using GTX00626 RyR2 (phospho Ser2814) antibody.
P-peptide: phospho-peptide
N-peptide: non-phospho-peptide
Peptides concentration : 1μg/ml

GTX00626 WB Image

WB analysis of A431 cell lysate using GTX00626 RyR2 (phospho Ser2814) antibody.
Lane 1 : Primary antibody prior incubate with phospho-blocking peptide
Lane 2 : Primary antibody prior incubate with non-phospho-blocking peptide

GTX00626 IHC-P Image

IHC-P analysis of human thyroid cancer tissue using GTX00626 RyR2 (phospho Ser2814) antibody.
Antigen retrieval : Heat mediated antigen retrieval step in citrate buffer
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 419

Qty