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S100A6 antibody [CACY-100]

Cat. No. GTX11181

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CACY-100

Isotype

 IgG1

Application

 WB, IHC-P, IHC-Fr, IP

Reactivity

 Human, Rat, Goat, Bovine, Dog, Pig, Lizard
Package
100 μl ($399)
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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr 1:4,000
IP Assay dependent
Not tested in other applications.

Calculated MW

10 kDa. ( Note )

Positive Control

bovine tongue

Product Note

Recognizes an epitope located on S100A6 (Calcyclin in the old terminology) in a Ca2+ ion-dependent manner. The product does not react with other members of the EF-hand family such as calmodulin, parvalbumin, intestinal calcium-binding protein, S100A2 (S100L), caltropin, the α chain of S-100 (i.e. in S-100a and S-100ao), or the β chain (i.e. in S-100a and S-100b).

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Pig

Immunogen

Ca2+-binding proteins from pig stomach tissue

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_368827

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

S100 calcium binding protein A6 , 2A9 , 5B10 , CABP , CACY , PRA , S10A6

Cellular Localization

Cytoplasm

Background

This protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Database

Research Area

REFERENCE

Application Reference

Scheiter M et al. Mol Cell Proteomics 2013; 12 (5) : 1099-114 Proteome analysis of distinct developmental stages of human natural killer (NK) cells.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399