SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9]

Name: SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9]
Brand: GeneTex
SKU: GTX632604
Price: 329.00 USD
Rating: 5 (9 reviews)

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX632604

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in ELISA (ELISA). GTX632604

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Immunoprecipitation (IP). GTX632604

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Western Blot (WB). GTX632604

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in Flow cytometry (FACS). GTX632604

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC (Paraffin sections) (IHC-P). GTX632604

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX632604

Cat No. GTX632604

Reference 56

Host	Mouse
Clonality	Monoclonal
Clone Name	1A9
Isotype	IgG1
Application	WB, ICC/IF, IHC-P, FACS, IP, ELISA, EM, Sandwich ELISA, IHC-P (cell pellet)
Reactivity	SARS Coronavirus, SARS Coronavirus 2
Package	100 μl ($329), 25 μl ($169)

See all SARS-CoV-2 (COVID-19) Spike products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500-1:3000
ICC/IF	1:100-1:2000
IHC-P	Assay dependent
FACS	Assay dependent
IP	Assay dependent
ELISA	Assay dependent
EM	Assay dependent
Sandwich ELISA	Assay dependent
IHC-P (cell pellet)	Assay dependent
Note : Sandwich ELISA Capture : GTX632604, Detection: GTX635654/GTX135356/GTX635672/GTX135386/GTX135360

Not tested in other applications.

Product Note

This antibody detects both SARS-CoV spike and SARS-CoV-2 spike proteins (S2 subunit). Our internal testing indicates no cross-reactivity with MERS-CoV spike protein.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

SARS Coronavirus

Immunogen

The immunogen used to generate this antibody corresponds to SARS-CoV SΔ10 (within S2 domain) protein (1029-1192 a.a.). (SARS-CoV strain: Sin2774) The exact sequence is proprietary.

Purification

Affinity purified by Protein G.

Conjugation

Unconjugated

RRID

AB_2864418

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

2019-nCoV Spike , SARS-CoV-2 Spike , COVID-19 Spike

Research Area

DATA IMAGES

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunofluorescent analysis.
Sample: BHK-21 cells transfected with full-length SARS-CoV-2 spike were fixed in 4% paraformaldehyde at RT for 30 min.
Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:2000.

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant full-length SARS-CoV-2 spike (trimer) protein using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX635654 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant full-length SARS-CoV-2 spike (trimer) protein using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX635672 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 IP Image

Immunoprecipitation of SARS-CoV-2 Spike transfected 293T whole cell extracts using 2 μg of SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Western blot analysis was performed using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
EasyBlot HRP-conjugated anti mouse IgG antibody (GTX221667-01) was used to detect the primary antibody.

GTX632604 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

GTX632604 ELISA Image

Sandwich ELISA detection of non-transfected (GTX535673) and SARS-CoV-2 spike (full length) transfected (GTX535664) 293T whole cell extracts using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX135356 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 WB Image

Non-infected (–) and infected (+, 48h pl MOI 0.01) Caco-2 whole cell extracts were separated by SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.

GTX632604 ELISA Image

Indirect ELISA analysis was performed by coating plate with 50 μL of recombinant SARS-CoV-2 (COVID-19) spike S2 ECD protein at concentrations ranging from 0.0625 μg/mL to 4 μg/mL. The coated protein is detected with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) at 1 μg/mL. Mouse IgG antibody (HRP) (GTX213111-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 by immunofluorescent analysis.
Sample: Vero E6 cells were infected with SARS-CoV-2 (MOI of 1) and fixed with chilled methanol/acetone.
Green: SARS-CoV-2 infected Vero E6 cells stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Blue: Nuclei were counterstained with DAPI.

*From Zheng Z, et al. bioRxiv(2020). Shown under license agreement

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunofluorescent analysis.
Sample: Mock and SARS-CoV-2-transfected COS-7 cells were fixed in 4% paraformaldehyde for 10 min at room temperature.
Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).
Blue: Nuclei were counterstained with DAPI.

*From Zheng Z, et al. bioRxiv(2020). Shown under license agreement

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, mouse IgG Fc tag protein (GTX135684-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S2 antibody [HL237] (GTX635693) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 FACS Image

FACS analysis of 293T cells infected with recombinant vaccinia virus carrying the Spike gene using GTX632604 SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9].

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) Spike S2 (ECD) protein, human IgG Fc tag (GTX01559-pro) using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and Human IgG antibody (HRP) (1:200000) as detection antibody.

GTX632604 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

GTX632604 IHC-P Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis of infected human placenta.

GTX632604 ICC/IF Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] protein by immunofluorescent analysis.
Sample: Mock and transfected 293T cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green:SARS-CoV-2 (COVID-19) spike protein stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant SARS-CoV-2 (COVID-19) spike S2 ECD protein using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX135386 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 ELISA Image

Sandwich ELISA detection of non-transfected and transfected 293T whole cell extracts using GTX632604 as capture antibody at concentration of 5 μg/mL and GTX135360 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 IHC-P Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis of SARS-CoV-2 infected human lung.

The IHC-P was performed by HISTOWIZ.

GTX632604 IHC-P Image

GTX632604 ELISA Image

Sandwich ELISA detection of recombinant full-length SARS-CoV-2 spike (trimer) protein using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike RBD antibody (GTX135709) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 ELISA Image

Sandwich ELISA detection of non-transfected (GTX535673) and SARS-CoV-2 spike (full length) transfected (GTX535664) 293T whole cell extracts using SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) as capture antibody at concentration of 5 μg/mL and SARS-CoV-2 (COVID-19) Spike S1 antibody [HL6] (GTX635654) as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX632604 ELISA Image

GTX632604 IHC-P (cell pellet) Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV / SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis.
Sample: Paraffin-embedded SARS-CoV-2 (COVID-19) Spike FFPE Cell Pellet Block.
Red: SARS-CoV / SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.
Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV-2 (COVID-19) spike antibody (GTX135356) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX632604 IHC-P (cell pellet) Image

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] detects SARS-CoV-2 (COVID-19) spike protein by immunohistochemical analysis.
Sample: Mock (GTX435670) and SARS-CoV-2 (COVID-19) Spike transfected 293T cell FFPE Cell Pellet Block (GTX435640).
Red: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

Application Reference

Welsh E et al. Br J Dermatol 2021; (Epub) SARS-CoV-2 Spike Protein Positivity in Pityriasis Rosea-like and Urticaria-like Rashes of COVID-19.

Application : IHC-P

Rebendenne A et al. J Virol 2021; (Epub) SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells.

Application : WB

Ozono S et al. Nat Commun 2021; 12 (1) : 848 SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity.

Application : WB

Winstone H et al. J Virol 2021; (Epub) The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I interferon and IFITM2.

Application : WB

Tada T et al. bioRxiv 2021; (Epub) Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine-elicited antibodies.

Application : WB

Show More +

Submit a Reference

REVIEW

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] Cat No. GTX632604

Rating

( Average 5 based on 9 users reviews)

Application

Western Blot(WB)		( Average 5 based on 2 users reviews)
Immunocytochemistry/ Immunofluorescence(ICC/IF)		( Average 5 based on 3 users reviews)
IHC (Paraffin sections)(IHC-P)		( Average 5 based on 2 users reviews)
Flow cytometry(FACS)		( Average 5 based on 1 users reviews)

Date : Anonymous submitted on 02-Aug-2020

Score :

Application Tested : IHC-P

Sample Species : SARS-CoV-2

Sample : Human placenta tissue

Fixation : neutral buffered formalin, 25°C, 24Hr

Permeabilization /Antigen retrieval : Citrate buffer pH6, 97°C, 0.3Hr

Primary Antibody : 1:100, 25°C, 0.5Hr

Date : Anonymous submitted on 14-Jul-2020

Score :

Application Tested : FACS

Sample Species : SARS-CoV-2

Sample : Vero E6 cells infected with SARS-CoV-2 USA-WA1/2020

Fixation : 4% formaldehyde in PBS

Permeabilization /Antigen retrieval : BD Cytofix/Cytoperm

Primary Antibody : 1:100, 25°C, 0.5Hr

Date : Anonymous submitted on 21-Jun-2020

Score :

Application Tested : IHC-P

Sample Species : SARS-CoV-2

Sample : Human lung tissue

Blocking : 2% BSA + 5% donkey serum + 0.15% PBST, 25°C, 1Hr

Permeabilization /Antigen retrieval : 1% Triton, Sodium Citrate Buffer

Primary Antibody : 1:500, 4°C, 16Hr

Figure Note : Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).

Date : Anonymous submitted on 21-Jun-2020

Score :

Application Tested : ICC/IF

Sample Species : SARS-CoV-2

Sample : SARS-CoV-2 FL spike transfected HeLa cells

Primary Antibody : 1μg/ml, 4°C, 16Hr

Date : Mohamed Gadalla submitted on 19-Jun-2020

Score :

Application Tested : WB

Sample Species : SARS-CoV-2

Sample : 293T cells

Amount used : 25 μg

Blocking : 5% non-fat dry milk in PBST, 25°C, 1Hr

Primary Antibody : 1:1000, 4°C, 16Hr

Date : Anonymous submitted on 17-Jun-2020

Score :

Application Tested : ICC/IF

Sample Species : SARS-CoV-2

Sample : SARS-CoV-2 spike transfected 293T cells

Fixation : 4% PFA, 25°C, 0.5Hr

Primary Antibody : 1:200, 1°C, 25Hr

Anti-SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9]. GTX632604

Date : Anonymous submitted on 31-Mar-2020

Score :

Sample Species : SARS-CoV

Sample : SARS-CoV infected 293T cells

Amount used : 10 μg

Blocking : BSA, 1Hr

Primary Antibody : 1:1000, 25°C, 1Hr

Date : Anonymous submitted on 10-Mar-2020

Score :

Application Tested : ICC/IF

Sample Species : SARS-CoV-2

Sample : BHK-21 transfected with full-length SARS-CoV-2 spike

Fixation : PFA, 0.5Hr

Primary Antibody : 1:2000, 4°C, 4Hr

Figure Note : Green: SARS-CoV-2 (COVID-19) spike stained by SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] (GTX632604).

Date : Anonymous submitted on 01-Mar-2020

Score :

Application Tested : WB

Sample Species : SARS-CoV, SARS-CoV-2

Sample : SARS-CoV / SARS-CoV-2 infected Caco-2 cells

Amount used : 20 μg

Blocking : 5% milk in PBST, 20°C, 0.5Hr

Primary Antibody : 1:1000, 4°C, 16Hr

Show More +

Submit a Review

Application Reference

Biomedical Journal 2021; (Epub) Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.

Application : WB, ICC/IF

Di Teodoro G et al. Vet Microbiol 2021; 252:108933 SARS-CoV-2 replicates in respiratory ex vivo organ cultures of domestic ruminant species.

Application : IHC-P

Welsh E et al. Br J Dermatol 2021; (Epub) SARS-CoV-2 Spike Protein Positivity in Pityriasis Rosea-like and Urticaria-like Rashes of COVID-19.

Application : IHC-P

Rebendenne A et al. J Virol 2021; (Epub) SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells.

Application : WB

Ozono S et al. Nat Commun 2021; 12 (1):848 SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity.

Application : WB

Winstone H et al. J Virol 2021; (Epub) The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I interferon and IFITM2.

Application : WB

Eric Song et al. J Exp Med 2021; 218 (3):e20202135 Neuroinvasion of SARS-CoV-2 in human and mouse brain.

Application : IHC-P

Vandergaast R et al. bioRxiv 2020; (Epub) Development and validation of IMMUNO-COV?: a high-throughput clinical assay for detecting antibodies that neutralize SARS-CoV-2.

Application : WB

Gao C et al. bioRxiv 2020; (Epub) SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors.

Application : WB

Heaton BE et al. bioRxiv 2020; (Epub) SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2.

Application : ICC/IF

Oguntuyo KY et al. medRxiv 2020; (Epub) Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera.

Application : WB

Drayman N et al. bioRxiv 2020; (Epub) Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro.

Application : IHC-P

Olagnier D et al. Nat Commun 2020; 11 (1):4938 SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.

Application : WB

Dalskov L et al. EMBO Rep 2020;:e51252 SARS-CoV-2 evades immune detection in alveolar macrophages.

Application : WB

Pellegrini L et al. Cell Stem Cell 2020; 27 (6):951-961.e5 SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids.

Application : IHC-P

Katsura H et al. Cell Stem Cell 2020; 27 (6):890-904.e8 Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Li X et al. bioRxiv 2020; (Epub) Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models.

Application : IHC-P

Plescia CB et al. J Biol Chem 2020; (Epub) SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles.

Application : WB

Chiuppesi F et al. Nat Commun 2020; 11 (1):6121 Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform.

Application : FACS

Ng JH et al. Adv Chronic Kidney Dis 2020; 27 (5):365-376 Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19.

Application : IHC-P

Swann H et al. Sci Rep 2020; 10 (1):21877 Minimal system for assembly of SARS-CoV-2 virus like particles.

Application : EM

Kuo-Yen Huang et al. EMBO Mol Med 2020;:e12828 Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection.

Application : WB

Zhao CL et al. Hum Pathol 2020; (Epub) Pathological findings in the postmortem liver of COVID-19 patients.

Application : IHC-P

Jacob E Valk et al. J Perinatol. 2020;:1-3 Detection of SARS-CoV-2 in placental but not fetal tissues in the second trimester.

Application : IHC-P

Cristiane J Nunes-Santos et al. J Clin Immunol. 2020;:1-10 N-Glycan Modification in Covid-19 Pathophysiology: In vitro Structural Changes with Limited Functional Effects.

Application : WB

Congwen Wei et al. Nat Metab. 2020; (Epub) HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry.

Application : ICC/IF

Caroline B Plescia et al. J Biol Chem. 2020;:jbc.RA120.016148. SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles.

Application : WB, ICC/IF

Hattori SI et al. mBio 2020; 11 (4) GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection.

Application : ICC/IF

Boix-Vilanova J et al. Int J Dermatol 2020; (Epub) Grover-like skin eruption: another cutaneous manifestation in a COVID-19 patient.

Application : IHC-P

Ian Gallicano G et al. Gene Ther 2020; (Epub) Molecular targeting of vulnerable RNA sequences in SARS CoV-2: identifying clinical feasibility.

Application : WB, ICC/IF

Rossana Bussani et al. EBioMedicine 2020;:103104 Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology.

Laura Varela Barca et al. Interact Cardiovasc Thorac Surg 2020; (Epub) An unexplained death after routine cardiac surgery: how long have we dealt with coronavirus disease 2019?

Application : IHC-P

Carolina da S G Pedrosa et al. bioRxiv 2020;:2020.09.11.293951 Non-permissive SARS-CoV-2 infection of neural cells in the developing human brain and neurospheres.

Application : WB, IHC-P

Kumari G Lokugamage et al. J Virol. 2020;:JVI.01410-20 Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.

Application : WB

Hongjie Xia et al. Cell Rep. 2020; 33 (1):108234 Evasion of Type I Interferon by SARS-CoV-2.

Application : WB

Chiuppesi F et al. Res Sq 2020; Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform.

Application : FACS

Andina D et al. Pediatr Dermatol 2020; Suspected COVID-19-related reticulated purpura of the soles in an infant.

Application : IHC-P

Szabolcs M et al. Appl Immunohistochem Mol Morphol 2020; Identification of Immunohistochemical Reagents for In Situ Protein Expression Analysis of Coronavirus-associated Changes in Human Tissues.

Application : IHC-P

Thomas Mandel Clausen et al. Cell 2020; S0092-8674 (20):31230-7 SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.

Application : FACS

Jakob Matschke et al. Lancet Neurol. 2020; S1474-4422 (20):30308-2 Neuropathology of patients with COVID-19 in Germany: a post-mortem case series.

Application : IHC-P

Kellie J Goodlet et al. Transpl Infect Dis 2020;:e13480 COVID-19 in a Lung Transplant Recipient: Exploring the Diagnostic Role of Circulating Exosomes and the Clinical Impact of Advanced Immunosuppression.

Application : WB

T Gambichler et al. J Eur Acad Dermatol Venereol. 2020; (Epub) SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion.

Application : IHC-P

Alain C Borczuk et al. Mod Pathol. 2020; (Epub) COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City.

Application : IHC-P

Antonio Torrelo et al. Pediatr Dermatol. 2020;:10.1111/pde.14246. Erythema multiforme‐like lesions in children and COVID‐19.

Application : IHC-P

Appelberg S et al. Emerg Microbes Infect 2020; 9 (1):1748-1760 Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.

Mariano Carossino et al. Arch Virol 2020; 5:1-5 Detection of SARS-CoV-2 by RNAscope ® in situ hybridization and immunohistochemistry techniques.

Application : IHC-P

Christine J Ko et al. J Cutan Pathol . 2020; (Epub) Perniosis during the COVID-19 pandemic: Negative Anti-SARS-CoV-2 Immunohistochemistry in Six Patients and Comparison to Perniosis Before the Emergence of SARS-CoV-2.

Application : IHC-P

Benjamin T Bradley et al. Lancet 2020; S0140-6736 (20):31305-2 Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series.

Application : IHC-P

Satoru Kudose et al. J Am Soc Nephrol 2020;:ASN.2020060802 Kidney Biopsy Findings in Patients with COVID-19.

Application : IHC-P

Bianca Pulinx et al. Eur J Clin Microbiol Infect Dis 2020; 13:1-15 Vertical transmission of SARS-CoV-2 infection and preterm birth.

Application : IHC-P

Laura Prieto-Pérez et al. Mod Pathol 2020; (Epub) Histiocytic Hyperplasia With Hemophagocytosis and Acute Alveolar Damage in COVID-19 Infection.

Application : IHC-P

C Santonja et al. Br J Dermatol 2020; (Epub) COVID-19 Chilblain-Like Lesion: Immunohistochemical Demonstration of SARS-CoV-2 Spike Protein in Blood Vessel Endothelium and Sweat Gland Epithelium in a PCR-negative Patient.

Application : IHC-P

I Colmenero et al. Br J Dermatol 2020; (Epub) SARS-CoV-2 Endothelial Infection Causes COVID-19 Chilblains: Histopathological, Immunohistochemical and Ultraestructural Study of 7 Paediatric Cases.

Application : IHC-P

Clone Reference

Zhiqiang Zheng et al. 2020; (Epub) Monoclonal antibodies for the S2 subunit of spike of SARS-CoV cross-react with the newly-emerged SARS-CoV-2.

Application : ICC/IF

Reactivity : SARS Coronavirus 2

Kuo-Ming Lip et al. J Virol . 2006; 80 (2):941-50 Monoclonal Antibodies Targeting the HR2 Domain and the Region Immediately Upstream of the HR2 of the S Protein Neutralize in Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus.

Application : WB

Reactivity : SARS Coronavirus

SDS
PBS.pdf

Package	List Price ($)
100 μl	$ 329
25 μl	$ 169
Qty

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9]

Cat No. GTX632604

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Product Note

PROPERTIES

Form

Buffer

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

RRID

Note

TARGET

Synonyms

Research Area

DATA IMAGES

GTX632604 ICC/IF Image

GTX632604 ELISA Image

GTX632604 ELISA Image

GTX632604 IP Image

GTX632604 WB Image

GTX632604 ELISA Image

GTX632604 WB Image

GTX632604 ELISA Image

GTX632604 ICC/IF Image

GTX632604 ICC/IF Image

GTX632604 ELISA Image

GTX632604 FACS Image

GTX632604 ELISA Image

GTX632604 WB Image

GTX632604 IHC-P Image

GTX632604 ICC/IF Image

GTX632604 ELISA Image

GTX632604 ELISA Image

GTX632604 IHC-P Image

GTX632604 IHC-P Image

GTX632604 ELISA Image

GTX632604 ELISA Image

GTX632604 ELISA Image

GTX632604 IHC-P (cell pellet) Image

GTX632604 IHC-P (cell pellet) Image

REFERENCE

Application Reference

REVIEW

SARS-CoV / SARS-CoV-2 (COVID-19) spike antibody [1A9] Cat No. GTX632604

SARS-CoV-2 (COVID-19) Nucleocapsid Protein Sandwich ELISA Kit

SARS-CoV-2 (COVID-19) nucleocapsid antibody [HL5511]

SARS-CoV-2 (COVID-19) Spike S1 antibody [HL263]

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