GeneTex
United States (US)

SB 431542

GTX80003_18122009_386.jpg

Cat No. GTX80003

Application CC
PRODUCT

Product Description

SB431542 is a small molecule inhibitor of the TGF-β1 activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 and -7. SB431542 inhibits endogenous activin and TGF-β signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -61, 2. Watabe and colleagues (2003) reported that at a concentration of 1μM, SB431542 stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells3.
PROPERTIES

Form

Liquid

Buffer

DMSO

Storage

Store at -20ºC. Maintain under sterile conditions

Concentration

2 mM (Please refer to the vial label for the specific concentration.)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
DATA IMAGES
GTX80003_18122009_386.jpg

GTX80003 Image


Package List Price ($)
$ 89