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SB 431542

SB 431542. GTX80003

Cat No. GTX80003

Application CC
Package
500 μl ($89)
PRODUCT

Product Description

SB431542 is a small molecule inhibitor of the TGF-β1 activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 and -7. SB431542 inhibits endogenous activin and TGF-β signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -61, 2. Watabe and colleagues (2003) reported that at a concentration of 1μM, SB431542 stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells3.
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
CC Assay dependent
Not tested in other applications.
PROPERTIES

Form

Liquid

Buffer

DMSO

Storage

Store at -20ºC. Maintain under sterile conditions

Concentration

2 mM (Please refer to the vial label for the specific concentration.)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
DATA IMAGES
SB 431542. GTX80003

GTX80003 Image

10μg of GTX109135-pro Galectin 2 recombinant protein analyzed using SDS-PAGE and stained with coomassie blue and captured by black and white camera.

REFERENCE
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Package List Price ($)
$ 89