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SBDS antibody

Anti-SBDS antibody used in IHC (Paraffin sections) (IHC-P). GTX64702
Anti-SBDS antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64702
Anti-SBDS antibody used in Western Blot (WB). GTX64702

Cat. No. GTX64702

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all SBDS products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SBDS (NP_057122.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SBDS ribosome maturation factor , CGI-97 , SDS , SWDS

Cellular Localization

Cytoplasm,nucleoplasm,Nucleolus

Background

This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jan 2017]

Database

Research Area

DATA IMAGES

Anti-SBDS antibody used in IHC (Paraffin sections) (IHC-P). GTX64702

GTX64702 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX64702 SBDS antibody.
Dilution : 1:100

Anti-SBDS antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64702

GTX64702 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX64702 SBDS antibody.
Blue : DAPI

Anti-SBDS antibody used in Western Blot (WB). GTX64702

GTX64702 WB Image

WB analysis of various sample lysates using GTX64702 SBDS antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399