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SCARA5 antibody

Anti-SCARA5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85270
Anti-SCARA5 antibody used in Western Blot (WB). GTX85270
Anti-SCARA5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85270

Cat. No. GTX85270

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all SCARA5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
ICC/IF 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

Hep G2 Cell Slide(GTX25530) , Human Spleen Tissue Lysate(GTX27921)

Product Note

At least four isoforms of SCARA5 are known to exist; this antibody will detect all four isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SCARA5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SCARA5.The immunogen is located within amino acids 350 - 400 of SCARA5.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_10723521

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

scavenger receptor class A member 5 , NET33 , Tesr

Cellular Localization

Cell membrane

Background

Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains that collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery. At least four isoforms of SCARB1 are known to exist.

Database

Research Area

DATA IMAGES

Anti-SCARA5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85270

GTX85270 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX85270 SCARA5 antibody.
Working concentration : 20 μg/ml

Anti-SCARA5 antibody used in Western Blot (WB). GTX85270

GTX85270 WB Image

WB analysis of human liver tissue lysate using GTX85270 SCARA5 antibody.
Working concentration : 1 μg/ml

Anti-SCARA5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85270

GTX85270 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX85270 SCARA5 antibody.
Working concentration : 2.5 μg/ml

REFERENCE

Application Reference

Huang SC et al. EMBO Mol Med 2017; (Epub) TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399