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SDC2 antibody

Anti-SDC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX12157
Anti-SDC2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX12157
Anti-SDC2 antibody used in Western Blot (WB). GTX12157

Cat. No. GTX12157

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr

Reactivity

 Human
Package
100 μg ($419)
See all SDC2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
IHC-P 0.5-1μg/ml
IHC-Fr 0.5-1μg/ml
Not tested in other applications.

Calculated MW

22.16 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA

Preservative

0.025% Thimerosal, 0.025% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Syndecan 2(105-122aa EETDKEKVHLSDSERKMD).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2885568

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Membrane

Background

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SDC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX12157

GTX12157 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX12157 SDC2 antibody.

Anti-SDC2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX12157

GTX12157 IHC-Fr Image

IHC-Fr analysis of human placenta tissue using GTX12157 SDC2 antibody.

Anti-SDC2 antibody used in Western Blot (WB). GTX12157

GTX12157 WB Image

WB analysis of various samples using GTX12157 SDC2 antibody.
Lane 1 : HepG2 cell lysate
Lane 2 : A549 cell lysate
Lane 3 : U87 cell lysate
Lane 4 : SKOV Cell ysate
Lane 5 : Jurkat cell lysate

REFERENCE

Application Reference

Niu F et al. Cancer Epidemiol Biomarkers Prev 2017; (Epub) Stool DNA Test of Methylated syndecan-2 for the Early Detection of Colorectal Neoplasia.
Application : WB, IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Thimerosal.pdf
Package List Price ($)
$ 419