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SDF1 beta antibody

Anti-SDF1 beta antibody used in Western Blot (WB). GTX45118

Cat. No. GTX45118

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP, IHC

Reactivity

 Mouse, Rat
Package
100 μg ($399)
See all SDF1 beta products

APPLICATION

Application Note

For WB: Use at a dilution of 1:1,000. For IP: Use at a dilution of 1:300 - 1:500. For IHC: Use at a dilution of 1:100 - 1:500. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

11 kDa. ( Note )

Product Note

CXCL12 in transfected cells

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Recombinant protein - mouse CXCL12

Purification

Protein A affinity purified
From polyclonal serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Chemokine (C-X-C Motif) Ligand 12 , Pbsf , Scyb12 , Sdf1 , Tlsf , Tpar1 , Cxcl12

Background

CXCL12, Stromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).

Research Area

DATA IMAGES

Anti-SDF1 beta antibody used in Western Blot (WB). GTX45118

GTX45118 WB Image

Detection of rat recombinant SDF-1 beta in transfected cells by WB.

REFERENCE

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399