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SDHB antibody [EP288]

Cat No. GTX01818

Host

Rabbit

Clonality

Monoclonal

Clone Name

EP288

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($659)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:25-1:100

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.

Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

Gastrointestinal stromal tumor (GIST)

PROPERTIES

Form

Liquid

Buffer

Culture supernatant diluted in 0.2% BSA and 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A recombinant protein corresponding to human SDHB protein

Purification

unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

succinate dehydrogenase complex iron sulfur subunit B , CWS2 , IP , PGL4 , SDH , SDH1 , SDH2 , SDHIP

Background

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for SDHB antibody [EP288] (GTX01818). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for SDHB antibody [EP288] (GTX01818). Be the first to share your experience with this product.