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SDHB antibody [HL2251]

Recombinant antibody
Anti-SDHB antibody [HL2251] used in IHC (Paraffin sections) (IHC-P). GTX638300
Anti-SDHB antibody [HL2251] used in IHC (Paraffin sections) (IHC-P). GTX638300
Anti-SDHB antibody [HL2251] used in Western Blot (WB). GTX638300
Anti-SDHB antibody [HL2251] used in IHC (Paraffin sections) (IHC-P). GTX638300

Cat. No. GTX638300

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2251

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat, Dog
Package
100 μl ($399),
25 μl ($169)
See all SDHB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human SDHB.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

succinate dehydrogenase complex iron sulfur subunit B , CWS2 , IP , PGL4 , SDH , SDH1 , SDH2 , SDHIP

Background

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SDHB antibody [HL2251] used in IHC (Paraffin sections) (IHC-P). GTX638300

GTX638300 IHC-P Image

SDHB antibody [HL2251] detects SDHB protein by immunohistochemical analysis.
Sample: Paraffin-embedded rat tissues.
SDHB stained by SDHB antibody [HL2251] (GTX638300) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-SDHB antibody [HL2251] used in IHC (Paraffin sections) (IHC-P). GTX638300

GTX638300 IHC-P Image

SDHB antibody [HL2251] detects SDHB protein by immunohistochemical analysis.
Sample: Paraffin-embedded mouse tissues.
SDHB stained by SDHB antibody [HL2251] (GTX638300) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-SDHB antibody [HL2251] used in Western Blot (WB). GTX638300

GTX638300 WB Image

Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with SDHB antibody [HL2251] (GTX638300) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SDHB antibody [HL2251] used in IHC (Paraffin sections) (IHC-P). GTX638300

GTX638300 IHC-P Image

SDHB antibody [HL2251] detects SDHB protein at mitochondria by immunohistochemical analysis.
Sample: Paraffin-embedded dog brain.
SDHB stained by SDHB antibody [HL2251] (GTX638300) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations