GeneTex
  • Country / Location Selection

United States (US)

SDHB blocking peptide

Cat No. GTX89491-PEP

Species

Human
Package
100 μg ($239)

APPLICATION

Product Note

The peptide was used in the production of GTX89491.

PROPERTIES

Form

Lyophilized powder

Buffer

Lyophilized from 5% (v/v) acetonitrile/H₂O. Reconstitute pellet in 200μl distilled water to obtain a 0.5mg/ml peptide solution.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

C-ATYKEKKASV

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Succinate Dehydrogenase Complex Iron Sulfur Subunit B , Cws2 , Ip , Pgl4 , Sdh , Sdh1 , Sdh2 , Sdhip , Sdhb

Background

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

There are currently no references for SDHB blocking peptide (GTX89491-PEP). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for SDHB blocking peptide (GTX89491-PEP). Be the first to share your experience with this product.