GeneTex

  • Country / Location Selection

United States (US)

SEC23B antibody

Cat. No. GTX82432

Reference 1

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
50 μg ($519)
See all SEC23B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
Not tested in other applications.

Calculated MW

86 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Immunogen Sequence: GI # 14591926, sequence 219-530 Recombinant sec23 (S. cerevisiae) homolog B

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Sec23 homolog B, coat complex II component , CDA-II , CDAII , CDAN2 , CWS7 , HEMPAS , hSec23B

Cellular Localization

Endoplasmic reticulum membrane,Cytoplasm, cytosol

Background

Component of the COPII coat. that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory. plasma membrane. and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (By similarity). The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Database

Research Area

REFERENCE

Application Reference

Jung J et al. J Cell Biol 2022; 221 (8) Regulation of the COPII secretory machinery via focal adhesions and extracellular matrix signaling.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for SEC23B antibody (GTX82432). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519