GeneTex
United States (US)

SEC62 antibody

GTX31455_1074_IHC-P_20180221_18121410_423.jpg
GTX31455_1075_IHC-P_20180221_18121410_145.jpg
GTX31455_2648_WB_20180221_18121410_265.jpg

Cat No. GTX31455

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

Positive Control

Rat Brain Tissue Lysate(GTX27942)

Specificity/Sensitivity

SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SEC62 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SEC62.The immunogen is located within amino acids 270 - 320 of SEC62.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Sec62 Homolog, Preprotein Translocation Factor,Dtrp1,Htp1,Tloc1,Tp-1,Sec62

Background

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX31455_1074_IHC-P_20180221_18121410_423.jpg

GTX31455 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31455 SEC62 antibody.
Working concentration : 5 μg/ml

GTX31455_1075_IHC-P_20180221_18121410_145.jpg

GTX31455 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31455 SEC62 antibody.
Working concentration : 20 μg/ml

GTX31455_2648_WB_20180221_18121410_265.jpg

GTX31455 WB Image

WB analysis of rat brain tissue lysate using GTX31455 SEC62 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Package List Price ($)
$ 329