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SENP1 antibody

Anti-SENP1 antibody used in Western Blot (WB). GTX20254

Cat. No. GTX20254

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all SENP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 3 - 5 μg/ml
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This antibody was developed against a synthetic peptide corresponding to aa 578-590 of human SENP1.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SUMO specific peptidase 1 , SuPr-2

Cellular Localization

Nucleus,Cytoplasm

Background

The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-SENP1 antibody used in Western Blot (WB). GTX20254

GTX20254 WB Image

WB analysis of (A) Daudi, (B) HeLa and (C) NIH-3T3 cell lysates using GTX20254 SENP1 antibody.

REFERENCE

Application Reference

Zhao X et al. Cell Rep 2020; 33 (1) : 108191 PKCε SUMOylation Is Required for Mediating the Nociceptive Signaling of Inflammatory Pain.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399