APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
brain , kidney , rat liver , testis
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human SENP3
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
SUMO specific peptidase 3 , SMT3IP1 , SSP3 , Ulp1
Cellular Localization
nucleoplasm,Cytoplasm,Nucleolus
Background
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
Database
Research Area
DATA IMAGES
|
GTX45298 WB Image
WB analysis of rat liver, brain, testis, and kidney tissue using GTX45298 SENP3 antibody at 1:1000.
Lane :
1 : Rat Liver cells (200ug)
2 : Rat Brain cells (200ug)
3 : Rat Testis cells (200ug)
4 : Rat Kidney cells (200ug)
|
|
GTX45298 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX45298 SENP3 antibody at 2μg/ml.
|
REFERENCE
There are currently no references for SENP3 antibody, N-term (GTX45298). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SENP3 antibody, N-term (GTX45298). Be the first to share your experience with this product.