APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 - 1:2000 |
1:50 - 1:200 |
1:100 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant funsion protein containing a sequence corresponding to amino acids 1-369 of human SEPT5 (NP_002679.2).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
septin 5 , CDCREL , CDCREL-1 , CDCREL1 , H5 , HCDCREL-1 , PNUTL1
Cellular Localization
Cytoplasm,Cytoplasm, cytoskeleton
Background
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]
Database
Research Area
DATA IMAGES
|
GTX66146 ICC/IF Image
ICC/IF analysis of U2OS cells using GTX66146 SEPT5 antibody. Blue : DAPI Dilution : 1:100
|
|
GTX66146 WB Image
WB analysis of various sample lysates using GTX66146 SEPT5 antibody. Dilution : 1:3000 Loading : 25μg per lane
|
|
GTX66146 IHC-P Image
IHC-P analysis of rat brain tissue using GTX66146 SEPT5 antibody. Dilution : 1:100
|
|
GTX66146 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX66146 SEPT5 antibody. Dilution : 1:100
|
REFERENCE
There are currently no references for SEPT5 antibody (GTX66146). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SEPT5 antibody (GTX66146). Be the first to share your experience with this product.