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SERCA2 ATPase antibody

Anti-SERCA2 ATPase antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55790
Anti-SERCA2 ATPase antibody used in Western Blot (WB). GTX55790
Anti-SERCA2 ATPase antibody used in IHC (Paraffin sections) (IHC-P). GTX55790
Anti-SERCA2 ATPase antibody used in IHC (Paraffin sections) (IHC-P). GTX55790

Cat. No. GTX55790

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all SERCA2 ATPase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

115 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 111-253 of human ATP2A2 (NP_733765.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 , ATP2B , DAR , DD , SERCA2

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-SERCA2 ATPase antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55790

GTX55790 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX55790 SERCA2 ATPase antibody.
Blue : DAPI

Anti-SERCA2 ATPase antibody used in Western Blot (WB). GTX55790

GTX55790 WB Image

WB analysis of various sample lysates using GTX55790 SERCA2 ATPase antibody.
Dilution : 1:500
Loading : 25μg per lane

Anti-SERCA2 ATPase antibody used in IHC (Paraffin sections) (IHC-P). GTX55790

GTX55790 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX55790 SERCA2 ATPase antibody.
Dilution : 1:100

Anti-SERCA2 ATPase antibody used in IHC (Paraffin sections) (IHC-P). GTX55790

GTX55790 IHC-P Image

IHC-P analysis of rat brain tissue using GTX55790 SERCA2 ATPase antibody.
Dilution : 1:100

REFERENCE

Application Reference

?cie?y?ska A et al. Int J Mol Sci 2023; 24 (9) Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes.
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399