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SETDB1 antibody [5H6A12]

Anti-SETDB1 antibody [5H6A12] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80408
Anti-SETDB1 antibody [5H6A12] used in Western Blot (WB). GTX80408

Cat. No. GTX80408

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5H6A12

Isotype

 IgG1

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Monkey
Package
100 μl ($399)
See all SETDB1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

143 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human SETDB1 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SET domain bifurcated histone lysine methyltransferase 1 , ESET , H3-K9-HMTase4 , KG1T , KMT1E , TDRD21

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]

Database

Research Area

DATA IMAGES

Anti-SETDB1 antibody [5H6A12] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80408

GTX80408 ICC/IF Image

ICC/IF analysis of LOVO cells using GTX80408 SETDB1 antibody [5H6A12].
Green : SETDB1
Red: Actin filaments

Anti-SETDB1 antibody [5H6A12] used in Western Blot (WB). GTX80408

GTX80408 WB Image

WB analysis of MCF-7 (1),T47D (2), HEK293 (3), JURKAT (4), NIH3T3 (5), F9 (6), RAW246.7 (7) and Cos7 (8) cell lysate using GTX80408 SETDB1 antibody [5H6A12].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399