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SETDB1 antibody

Anti-SETDB1 antibody used in Western Blot (WB). GTX33492
Anti-SETDB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33492
Anti-SETDB1 antibody used in Western Blot (WB). GTX33492

Cat. No. GTX33492

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all SETDB1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

143 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-397 of human SETDB1 (NP_001230420.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SET domain bifurcated histone lysine methyltransferase 1 , ESET , H3-K9-HMTase4 , KG1T , KMT1E , TDRD21

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]

Database

Research Area

DATA IMAGES

Anti-SETDB1 antibody used in Western Blot (WB). GTX33492

GTX33492 WB Image

WB analysis of 293T cell lysate using GTX33492 SETDB1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-SETDB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33492

GTX33492 IHC-P Image

IHC-P analysis of rat brain tissue using GTX33492 SETDB1 antibody.
Dilution : 1:100

Anti-SETDB1 antibody used in Western Blot (WB). GTX33492

GTX33492 WB Image

WB analysis of various sample lysates using GTX33492 SETDB1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399