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SETDB2 antibody [N1], N-term

Anti-SETDB2 antibody [N1], N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX108086

Cat No. GTX108086

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF

Reactivity

Human
Package
100 μl ($329),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1:100-1:2000
Not tested in other applications.

Calculated MW

82 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SETDB2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1241318

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

SET domain bifurcated histone lysine methyltransferase 2 , C13orf4 , CLLD8 , CLLL8 , KMT1F

Cellular Localization

Nucleus

Background

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-SETDB2 antibody [N1], N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX108086

GTX108086 ICC/IF Image

SETDB2 antibody [N1], N-term detects SETDB2 protein at nucleus by immunofluorescent analysis.
Sample: HCT 116 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: SETDB2 protein stained by SETDB2 antibody [N1], N-term (GTX108086) diluted at 1:2000.
Blue: Hoechst 33342 staining.

REFERENCE

There are currently no references for SETDB2 antibody [N1], N-term (GTX108086). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for SETDB2 antibody [N1], N-term (GTX108086). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf