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SGCE antibody

Anti-SGCE antibody used in IHC (Paraffin sections) (IHC-P). GTX33494
Anti-SGCE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33494
Anti-SGCE antibody used in Western Blot (WB). GTX33494

Cat. No. GTX33494

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all SGCE products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human SGCE (NP_003910.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887715

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sarcoglycan epsilon , DYT11 , ESG , epsilon-SG

Cellular Localization

Cytoplasm, cytoskeleton,Cell projection, dendrite,Golgi apparatus

Background

This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. [provided by RefSeq, Oct 2016]

Database

Research Area

DATA IMAGES

Anti-SGCE antibody used in IHC (Paraffin sections) (IHC-P). GTX33494

GTX33494 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX33494 SGCE antibody.
Dilution : 1:200

Anti-SGCE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33494

GTX33494 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX33494 SGCE antibody.
Blue : DAPI

Anti-SGCE antibody used in Western Blot (WB). GTX33494

GTX33494 WB Image

WB analysis of various sample lysates using GTX33494 SGCE antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Perez-Ortiz AC et al. Int J Mol Sci 2019; 20 (21) Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration.
Application : IHC-P
Reactivity : Mouse
Estrada-Mena FJ et al. Neurosci Lett 2017; 658 : 142-149 Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice.
Application : WB
Reactivity : Mouse
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399