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SH3BP1 antibody, C-term

Anti-SH3BP1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX10103
Anti-SH3BP1 antibody, C-term used in Western Blot (WB). GTX10103

Cat No. GTX10103

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
ICC/IF Assay dependent
IHC-P 0.3μg/ml

Note :

IHC-P
Human Kidney stains the cytoplasm of lymphoid cells in the interstitial parenchyma and of lymphocytes in a glomerulus.

Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX10103-PEP).

PROPERTIES

Form

Liquid

Buffer

TBS pH7.3, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-PQPRPRSLASETN, from the C Terminus of the protein sequence according to NP_061830.3.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

SH3 domain binding protein 1 , ARHGAP43

Cellular Localization

Nucleus , Cytoplasm, cytosol

Background

This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues. [provided by RefSeq, Mar 2017]

Database

DATA IMAGES

Anti-SH3BP1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX10103

GTX10103 IHC-P Image

IHC-P analysis of human Kidnay using GTX10103 SH3BP1 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 0.3μg/ml
A) in the interstitial parenchyma of the kidney. B) in a glomerulus of the kidney

Anti-SH3BP1 antibody, C-term used in Western Blot (WB). GTX10103

GTX10103 WB Image

WB analysis of human brain lysate using GTX10103 SH3BP1 antibody, C-term.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for SH3BP1 antibody, C-term (GTX10103). Be the first to share your publications with this product.

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 369