APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1/500 - 1/2000 |
| 1/200 - 1/1000 |
| 1/200 - 1/1000 |
| 1/200 - 1/400 |
| 1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified recombinant fragment of human SHP2 (AA: 263-329) expressed in E. Coli.
Purification
Protein G Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
protein tyrosine phosphatase non-receptor type 11 , BPTP3 , CFC , JMML , METCDS , NS1 , PTP-1D , PTP2C , SH-PTP2 , SH-PTP3 , SHP2
Cellular Localization
Cytoplasm,Nucleus
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Database
Research Area
DATA IMAGES
![Anti-SHP2 antibody [6D9] used in Flow cytometry (FACS). GTX60640](/templates/default/js/lightbox/images/loading.gif "Anti-SHP2 antibody [6D9] used in Flow cytometry (FACS). GTX60640")
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GTX60640 FACS Image
FACS analysis of HepG2 cells using GTX60640 SHP2 antibody [6D9].
Green : SHP2
Red : negative control
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GTX60640 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX60640 SHP2 antibody [6D9].
Green : SHP2
Blue: DRAQ5 fluorescent DNA dye
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GTX60640 IHC-P Image
IHC-P analysis of breast cancer tissue using GTX60640 SHP2 antibody [6D9].
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GTX60640 WB Image
WB analysis of human SHP2 recombinant protein using GTX60640 SHP2 antibody [6D9].
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GTX60640 IHC-P Image
IHC-P analysis of rectum cancer tissue using GTX60640 SHP2 antibody [6D9].
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GTX60640 ELISA Image
ELISA analysis of antigen using GTX60640 SHP2 antibody [6D9].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng
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REFERENCE
There are currently no references for SHP2 antibody [6D9] (GTX60640). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SHP2 antibody [6D9] (GTX60640). Be the first to share your experience with this product.
![Anti-SHP2 antibody [6D9] used in Flow cytometry (FACS). GTX60640](/upload/website/prouct_img/small/GTX60640/GTX60640_20170912_FACS_w_23061123_781.webp "Anti-SHP2 antibody [6D9] used in Flow cytometry (FACS). GTX60640")
![Anti-SHP2 antibody [6D9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60640](/upload/website/prouct_img/small/GTX60640/GTX60640_20170912_ICCIF_w_23061123_723.webp "Anti-SHP2 antibody [6D9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60640")
![Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640](/upload/website/prouct_img/small/GTX60640/GTX60640_20170912_IHC-P_w_23061123_730.webp "Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640")
![Anti-SHP2 antibody [6D9] used in Western Blot (WB). GTX60640](/upload/website/prouct_img/small/GTX60640/GTX60640_20170912_WB_w_23061123_285.webp "Anti-SHP2 antibody [6D9] used in Western Blot (WB). GTX60640")
![Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640](/upload/website/prouct_img/small/GTX60640/GTX60640_20170912_IHC-P_1_w_23061123_570.webp "Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640")
![Anti-SHP2 antibody [6D9] used in ELISA (ELISA). GTX60640](/upload/website/prouct_img/small/GTX60640/GTX60640_20170912_ELISA_w_23061123_254.webp "Anti-SHP2 antibody [6D9] used in ELISA (ELISA). GTX60640")
![Anti-SHP2 antibody [6D9] used in Flow cytometry (FACS). GTX60640](/upload/website/prouct_img/normal/GTX60640/GTX60640_20170912_FACS_w_23061123_781.webp "Anti-SHP2 antibody [6D9] used in Flow cytometry (FACS). GTX60640")
![Anti-SHP2 antibody [6D9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60640](/upload/website/prouct_img/normal/GTX60640/GTX60640_20170912_ICCIF_w_23061123_723.webp "Anti-SHP2 antibody [6D9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60640")
![Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640](/upload/website/prouct_img/normal/GTX60640/GTX60640_20170912_IHC-P_w_23061123_730.webp "Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640")
![Anti-SHP2 antibody [6D9] used in Western Blot (WB). GTX60640](/upload/website/prouct_img/normal/GTX60640/GTX60640_20170912_WB_w_23061123_285.webp "Anti-SHP2 antibody [6D9] used in Western Blot (WB). GTX60640")
![Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640](/upload/website/prouct_img/normal/GTX60640/GTX60640_20170912_IHC-P_1_w_23061123_570.webp "Anti-SHP2 antibody [6D9] used in IHC (Paraffin sections) (IHC-P). GTX60640")
![Anti-SHP2 antibody [6D9] used in ELISA (ELISA). GTX60640](/upload/website/prouct_img/normal/GTX60640/GTX60640_20170912_ELISA_w_23061123_254.webp "Anti-SHP2 antibody [6D9] used in ELISA (ELISA). GTX60640")