GeneTex

  • Country / Location Selection

United States (US)

SHP2 antibody

Orthogonal
Anti-SHP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX50624
Anti-SHP2 antibody used in Western Blot (WB). GTX50624
Anti-SHP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50624

Cat. No. GTX50624

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all SHP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:200
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around aa.578~582 (R-V-Y-E-N) derived from human SHP2.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase non-receptor type 11 , BPTP3 , CFC , JMML , METCDS , NS1 , PTP-1D , PTP2C , SH-PTP2 , SH-PTP3 , SHP2

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES

Anti-SHP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX50624

GTX50624 IHC-P Image

Orthogonal

IHC-P analysis of human breast carcinoma tissue using GTX50624 SHP2 antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-SHP2 antibody used in Western Blot (WB). GTX50624

GTX50624 WB Image

Orthogonal

WB analysis of extracts from 293 cells using GTX50624 SHP2 antibody.

Anti-SHP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50624

GTX50624 ICC/IF Image

Orthogonal

ICC/IF analysis of methanol-fixed HeLa cells using GTX50624 SHP2 antibody.

REFERENCE

There are currently no references for SHP2 antibody (GTX50624). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for SHP2 antibody (GTX50624). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399