GeneTex
United States (US)

SIPA1 antibody

GTX31846_375_IHC-P_20180221_18121410_801.jpg
GTX31846_2998_WB_20180221_18121410_661.jpg

Cat No. GTX31846

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

112 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

Specificity/Sensitivity

At least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1.The immunogen is located within amino acids 40 - 90 of SIPA1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Signal-Induced Proliferation-Associated 1,Spa1,Sipa1

Background

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX31846_375_IHC-P_20180221_18121410_801.jpg

GTX31846 IHC-P Image

IHC-P analysis of human brain tissue using GTX31846 SIPA1 antibody.
Working concentration : 20 μg/ml

GTX31846_2998_WB_20180221_18121410_661.jpg

GTX31846 WB Image

WB analysis of human brain tissue lysate using GTX31846 SIPA1 antibody.
Working concentration : 1 μg/ml

Package List Price ($)
$ 329