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SIPA1 antibody

Anti-SIPA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31846
Anti-SIPA1 antibody used in Western Blot (WB). GTX31846

Cat. No. GTX31846

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all SIPA1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

112 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

Product Note

At least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1.The immunogen is located within amino acids 40 - 90 of SIPA1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal-induced proliferation-associated 1 , SPA1

Cellular Localization

Nucleus

Background

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SIPA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31846

GTX31846 IHC-P Image

IHC-P analysis of human brain tissue using GTX31846 SIPA1 antibody.
Working concentration : 20 μg/ml

Anti-SIPA1 antibody used in Western Blot (WB). GTX31846

GTX31846 WB Image

WB analysis of human brain tissue lysate using GTX31846 SIPA1 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399