APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
786-O , human fetal thymus
PROPERTIES
Form
Liquid
Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human SIRT1.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
sirtuin 1 , SIR2 , SIR2L1 , SIR2alpha
Cellular Localization
Cytoplasm,Nucleus,Mitochondrion
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Database
Research Area
DATA IMAGES
|
GTX30870 WB Image
WB analysis of human fetal thymus tissue using GTX30870 Sirt1 antibody at 0.5μg/ml.
|
|
GTX30870 WB Image
WB analysis of 786-O cells using GTX30870 Sirt1 antibody at 1μg/ml.
|
REFERENCE
There are currently no references for SIRT1 antibody, N-term (GTX30870). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SIRT1 antibody, N-term (GTX30870). Be the first to share your experience with this product.
![Anti-Cyclin D1 antibody [N1C3] used in Western Blot (WB). GTX108624](/upload/website/prouct_img/small/GTX108624/GTX108624_43754_20191108_WB_KO_watermark_20092220_924.jpg "Anti-Cyclin D1 antibody [N1C3] used in Western Blot (WB). GTX108624")
