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SIRT1 antibody

Anti-SIRT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32875
Anti-SIRT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32875

Cat No. GTX32875

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P, IP

Reactivity

Human, Mouse
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50 - 1:200
IP Assay dependent
Not tested in other applications.

Calculated MW

82 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide of human SIRT1

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

sirtuin 1 , SIR2 , SIR2L1 , SIR2alpha

Cellular Localization

Cytoplasm,Nucleus,Mitochondrion

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Database

Research Area

DATA IMAGES

Anti-SIRT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32875

GTX32875 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX32875 SIRT1 antibody.
Dilution : 1:100

Anti-SIRT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32875

GTX32875 IHC-P Image

IHC-P analysis of human stomach tissue using GTX32875 SIRT1 antibody.
Dilution : 1:100

REFERENCE

REVIEW

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Package List Price ($)
$ 329