APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1 - 2 μg/mL |
| 2.5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Mouse Brain Tissue Lysate(GTX27934)
PROPERTIES
Form
Liquid
Buffer
PBS with 0.02% sodium azide.
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
SIRT2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of the human SIRT2.The immunogen is located within the last 50 amino acids of SIRT2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
sirtuin 2 , SIR2 , SIR2L , SIR2L2
Cellular Localization
Nucleus,Cytoplasm,Cytoplasm, cytoskeleton
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
Database
Research Area
DATA IMAGES
|
GTX31335 WB Image
WB analysis of mouse brain tissue lysate using GTX31335 SIRT2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
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GTX31335 IHC-P Image
IHC-P analysis of human brain tissue using GTX31335 SIRT2 antibody.
Working concentration : 2.5 μg/ml
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GTX31335 IHC-P Image
IHC-P analysis of human brain tissue using GTX31335 SIRT2 antibody.
Working concentration : 5 μg/ml
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REFERENCE
There are currently no references for SIRT2 antibody (GTX31335). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SIRT2 antibody (GTX31335). Be the first to share your experience with this product.
