GeneTex
United States (US)

SIRT2 antibody

Anti-SIRT2 antibody used in Western Blot (WB). GTX31335
Anti-SIRT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31335
Anti-SIRT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31335

Cat No. GTX31335

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
See all SIRT2 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Mouse Brain Tissue Lysate(GTX27934)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SIRT2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of the human SIRT2.The immunogen is located within the last 50 amino acids of SIRT2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Sirtuin 2,Sir2,Sir2L,Sir2L2,Sirt2

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES
Anti-SIRT2 antibody used in Western Blot (WB). GTX31335

GTX31335 WB Image

WB analysis of mouse brain tissue lysate using GTX31335 SIRT2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
Anti-SIRT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31335

GTX31335 IHC-P Image

IHC-P analysis of human brain tissue using GTX31335 SIRT2 antibody.
Working concentration : 2.5 μg/ml
Anti-SIRT2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31335

GTX31335 IHC-P Image

IHC-P analysis of human brain tissue using GTX31335 SIRT2 antibody.
Working concentration : 5 μg/ml
Package List Price ($)
$ 329