GeneTex
United States (US)

SIRT2 antibody

GTX31336_2539_WB_20180221_18121410_420.jpg
GTX31336_944_IHC-P_20180221_18121410_408.jpg
GTX31336_945_IHC-P_20180221_18121410_732.jpg

Cat No. GTX31336

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 2.5 - 5 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SIRT2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of the human SIRT2.The immunogen is located within the first 50 amino acids of SIRT2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Sirtuin 2,Sir2,Sir2L,Sir2L2,Sirt2

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES
GTX31336_2539_WB_20180221_18121410_420.jpg

GTX31336 WB Image

WB analysis of human brain tissue lysate using GTX31336 SIRT2 antibody.
Working concentration : (A) 2.5 and (B) 5 μg/ml

GTX31336_944_IHC-P_20180221_18121410_408.jpg

GTX31336 IHC-P Image

IHC-P analysis of human brain tissue using GTX31336 SIRT2 antibody.
Working concentration : 2.5 μg/ml

GTX31336_945_IHC-P_20180221_18121410_732.jpg

GTX31336 IHC-P Image

IHC-P analysis of human brain tissue using GTX31336 SIRT2 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329