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SIRT3 antibody

Anti-SIRT3 antibody used in Western Blot (WB). GTX03711
Anti-SIRT3 antibody used in Western Blot (WB). GTX03711
Anti-SIRT3 antibody used in IHC (Paraffin sections) (IHC-P). GTX03711
Anti-SIRT3 antibody used in Western Blot (WB). GTX03711
Anti-SIRT3 antibody used in Western Blot (WB). GTX03711

Cat. No. GTX03711

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP, IHC

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all SIRT3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-100
IP Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 250-279 amino acids from the C-terminal region of human SIRT3.

Purification

Protein A purified followed by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sirtuin 3 , SIR2L3

Cellular Localization

Mitochondrion matrix

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SIRT3 antibody used in Western Blot (WB). GTX03711

GTX03711 WB Image

WB analysis of KG-1 cell line lysates (35ug/lane) using GTX03711 SIRT3 antibody.

Anti-SIRT3 antibody used in Western Blot (WB). GTX03711

GTX03711 WB Image

WB analysis of HepG2 cell line lysates (35ug/lane) using GTX03711 SIRT3 antibody.

Anti-SIRT3 antibody used in IHC (Paraffin sections) (IHC-P). GTX03711

GTX03711 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX03711 SIRT3 antibody.

Anti-SIRT3 antibody used in Western Blot (WB). GTX03711

GTX03711 WB Image

WB analysis of various sample lysates using GTX03711 SIRT3 antibody.
Lane 1 : human kidney lysate
Lane 2 : human liver lysate
Lane 3 : mouse liver lysate
Dilution : 1:2000
Loading : 20 μg per lane

Anti-SIRT3 antibody used in Western Blot (WB). GTX03711

GTX03711 WB Image

WB analysis of 293 and HepG2 cell lysates (from left to right) using GTX03711 SIRT3 antibody.
Dilution : 1:1000
Loading : 35ug per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399