GeneTex
United States (US)

SKP1 antibody

Anti-SKP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33502
Anti-SKP1 antibody used in Western Blot (WB). GTX33502

Cat No. GTX33502

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

19 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human SKP1 (NP_733779.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

S-Phase Kinase Associated Protein 1,Emc19,Ocp-Ii,Ocp2,Skp1A,Tceb1L,P19A,Skp1

Background

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-SKP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33502

GTX33502 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX33502 SKP1 antibody.
Dilution : 1:100

Anti-SKP1 antibody used in Western Blot (WB). GTX33502

GTX33502 WB Image

WB analysis of various samples using GTX33502 SKP1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329