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SLC17A5 antibody

Anti-SLC17A5 antibody used in Western Blot (WB). GTX115822
Anti-SLC17A5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX115822
Anti-SLC17A5 antibody used in IHC (Paraffin sections) (IHC-P). GTX115822

Cat. No. GTX115822

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all SLC17A5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Positive Control

Jurkat

Predict Reactivity

Rat, Rabbit, Sheep, Bovine, Chicken, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human SLC17A5. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10620717

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 17 member 5 , AST , ISSD , NSD , SD , SIALIN , SIASD , SLD

Cellular Localization

Lysosome membrane; Multi-pass membrane protein

Background

This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-SLC17A5 antibody used in Western Blot (WB). GTX115822

GTX115822 WB Image

Sample (30 ug of whole cell lysate)
A: Jurkat
10% SDS PAGE
GTX115822 diluted at 1:1000

Anti-SLC17A5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX115822

GTX115822 ICC/IF Image

SLC17A5 antibody detects SLC17A5 protein at Cytoplasm by immunofluorescent analysis.
Sample: HepG2 cells were fixed in -20ºC 100% MeOH for 5 min.
Green: SLC17A5 protein stained by SLC17A5 antibody (GTX115822) diluted at 1:500.
Blue: Hoechst 33343 staining.
Anti-SLC17A5 antibody used in IHC (Paraffin sections) (IHC-P). GTX115822

GTX115822 IHC-P Image

SLC17A5 antibody detects SLC17A5 protein at cytoplasm in mouse lung by immunohistochemical analysis.
Sample: Paraffin-embedded mouse lung.
SLC17A5 antibody (GTX115822) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

Application Reference

Eichner LJ et al. Cell Metab 2019; 29 (2) : 285-302.e7 Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169