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SLC26A5 antibody

Anti-SLC26A5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04615
Anti-SLC26A5 antibody used in Western Blot (WB). GTX04615

Cat. No. GTX04615

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all SLC26A5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:3000
ICC/IF 1:100-1:500
Not tested in other applications.

Calculated MW

81 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Sheep, Bovine, Chicken, Pig, Horse, Xenopus0

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human SLC26A5(Accession P58743), corresponding to amino acid residues A427-V477.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 26 member 5 , DFNB61 , PRES

Cellular Localization

Cell membrane

Background

This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]

Database

DATA IMAGES

Anti-SLC26A5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04615

GTX04615 ICC/IF Image

ICC/IF analysis of PFA-fixed HeLa cells using GTX04615 SLC25A5 antibody.
Red : Primary antibody
Green : Beta tubulin
Blue : DAPI
Permeabilization : 0.1% Triton X-100

Anti-SLC26A5 antibody used in Western Blot (WB). GTX04615

GTX04615 WB Image

WB analysis of Raji whole cell lysate using GTX04615 SLC26A5 antibody. The lane on the left was treated with blocking peptide.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399