50mM Sodium Borate, 0.05% Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.
Batch dependent (Please refer to the vial label for the specific concentration.)
A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [UniProt# O15431]
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
solute carrier family 31 member 1 , COPT1 , CTR1
Cell membrane; Multi-pass membrane protein
Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM]