GeneTex
United States (US)

SLC31A1 / CTR1 antibody

GTX30642_332_IHC-P_18121410_176.jpg
GTX30642_1611_IHC_18121410_680.jpg
GTX30642_220_ICC-IF_18121410_375.jpg

Cat No. GTX30642

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, IHC-Fr
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Xenopus
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 1:500
IHC-P 1:250
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

21 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate pH 7.0 - 8.0, 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [UniProt# O15431]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Solute Carrier Family 31 Member 1,Copt1,Ctr1,Slc31A1

Cellular Localization

Membrane

Background

Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM]

Database

DATA IMAGES
GTX30642_332_IHC-P_18121410_176.jpg

GTX30642 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX30642 SLC31A1 / CTR1 antibody.
Panel 1: human CTR1 staining of breast cancer tissue
Panel 2: human CTR1-antigen competition in breast cancer tissue

GTX30642_1611_IHC_18121410_680.jpg

GTX30642 ICC/IF Image

ICC/IF analysis of SLC31A1 / CTR1 overexpressing cells with (left) or without (right) peptide competition using GTX30642 SLC31A1 / CTR1 antibody.

GTX30642_220_ICC-IF_18121410_375.jpg

GTX30642 ICC/IF Image

ICC/IF analysis of NIH-3T3 cells using GTX30642 SLC31A1 / CTR1 antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI

Package List Price ($)
$ 349