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SLC39A6 antibody

Anti-SLC39A6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85131
Anti-SLC39A6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85131
Anti-SLC39A6 antibody used in Western Blot (WB). GTX85131

Cat. No. GTX85131

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all SLC39A6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Positive Control

Mouse Lung Tissue Lysate(GTX27933)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SLC39A6 antibody was raised against a 16 amino acid synthetic peptide near the center of human SLC39A6.The immunogen is located within amino acids 430 - 480 of SLC39A6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 39 member 6 , LIV-1 , ZIP6

Cellular Localization

Cell membrane

Background

The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

Database

Research Area

DATA IMAGES

Anti-SLC39A6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85131

GTX85131 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX85131 SLC39A6 antibody.
Working concentration : 20 μg/ml

Anti-SLC39A6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85131

GTX85131 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX85131 SLC39A6 antibody.
Working concentration : 5 μg/ml

Anti-SLC39A6 antibody used in Western Blot (WB). GTX85131

GTX85131 WB Image

WB analysis of mouse lung tissue lysate using GTX85131 SLC39A6 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399