GeneTex
United States (US)

SLC4A11 antibody

SLC4A11-antibody-GTX87741-WB-1_18122102_485.jpg

Cat No. GTX87741

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Specificity/Sensitivity

SLC4A11 Antibody detects endogenous levels of total SLC4A11 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human SLC4A11.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Sodium bicarbonate transporter-like protein 11, Solute carrier family 4, Bicarbonate transporterrelated protein 1, BTR1, Sodium borate cotransporter 1, Sodium bicarbonate transporterlike protein11, Bicarbonate transporterrelated protein1, Bicarbonate transporter-related protein 1, Solute carrier family4, Sodium borate cotransporter1, Sodium bicarbonate transporterlike protein 11, SLC4A11, NaBC1

Background

Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity). Involved in borate homeostasis. In the absence of borate, it functions as a Na(+) and OH(-)(H(+)) channel. In the presence of borate functions as an electrogenic Na(+) coupled borate cotransporter.
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Database

Research Area

DATA IMAGES
SLC4A11-antibody-GTX87741-WB-1_18122102_485.jpg

GTX87741 WB Image

Western blot analysis of extracts from NIH-3T3/RAW264.7/A549 cells, using SLC4A11 Antibody. The lane on the right is treated with the synthesized peptide.