GeneTex

  • Country / Location Selection

United States (US)

SLUG antibody

Overexpression
Anti-SLUG antibody used in IHC (Paraffin sections) (IHC-P). GTX30813
Anti-SLUG antibody used in Western Blot (WB). GTX30813
Anti-SLUG antibody used in Western Blot (WB). GTX30813
Anti-SLUG antibody used in Western Blot (WB). GTX30813
Anti-SLUG antibody used in Western Blot (WB). GTX30813

Cat. No. GTX30813

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($419)
See all SLUG products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5-2μg/ml
IHC-P Assay dependent

Note :

WB
This antibody detects a band of approximately 30kDa in 293 cell lysate.
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Product Note

This antibody detects Slug and is not cross-reactive with Snail.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

13 amino acid peptide sequence near the centre of human Slug.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_1952807

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

snail family transcriptional repressor 2 , SLUG , SLUGH , SLUGH1 , SNAIL2 , WS2D

Cellular Localization

Nucleus , Cytoplasm

Background

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SLUG antibody used in IHC (Paraffin sections) (IHC-P). GTX30813

GTX30813 IHC-P Image

IHC-P analysis of human kidney tissue using GTX30813 SLUG antibody.
Dilution : 20 μg/ml

Anti-SLUG antibody used in Western Blot (WB). GTX30813

GTX30813 WB Image

WB analysis of HEK293 cell lysate using GTX30813 SLUG antibody at 0.5(A), and 1(B) and 2(C) ug/ml.

Anti-SLUG antibody used in Western Blot (WB). GTX30813

GTX30813 WB Image

WB analysis of (A) human and (B) mouse kidney tissue lysate using GTX30813 SLUG antibody.
Dilution : 0.5 μg/ml

Anti-SLUG antibody used in Western Blot (WB). GTX30813

GTX30813 WB Image

Overexpression

The data was published in the journal PLoS One in 2017. PMID: 28683123

Anti-SLUG antibody used in Western Blot (WB). GTX30813

GTX30813 WB Image

Overexpression

The data was published in the journal PLoS One in 2017. PMID: 28683123

REFERENCE

Application Reference

Lee J et al. J Biol Chem 2018; (Epub) Fibroblast growth factor 2 induces proliferation and fibrosis via SNAI1-mediated activation of CDK2 and ZEB1 in corneal endothelium.
Lee AF et al. PLoS One 2017; 12 (7) : e0180383 Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for SLUG antibody (GTX30813). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419