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SMAD3 antibody [1E8]

Anti-SMAD3 antibody [1E8] used in IHC (Paraffin sections) (IHC-P). GTX34209

Cat No. GTX34209

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1E8

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μl ($319)
See all SMAD3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Specificity/Sensitivity

Smad3 Mouse Monoclonal Antibody (1E8) detects endogenous levels of SMAD3

PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic Peptide of Smad3

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Smad Family Member 3 , Hspc193 , Hst17436 , Jv15-2 , Lds1C , Lds3 , Madh3 , Smad3

Background

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

Database

Research Area

DATA IMAGES

Anti-SMAD3 antibody [1E8] used in IHC (Paraffin sections) (IHC-P). GTX34209

GTX34209 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcinoma Tissue using Smad3 Mouse Monoclonal Antibody diluted at 1:200.

REFERENCE

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REVIEW

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Package List Price ($)
$ 319