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SMRT antibody

Anti-SMRT antibody used in IHC (Paraffin sections) (IHC-P). GTX66517
Anti-SMRT antibody used in IHC (Paraffin sections) (IHC-P). GTX66517
Anti-SMRT antibody used in Western Blot (WB). GTX66517
Anti-SMRT antibody used in IHC (Paraffin sections) (IHC-P). GTX66517

Cat. No. GTX66517

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all SMRT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

274 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 670-900 of human NCOR2 (NP_006303.4).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor corepressor 2 , CTG26 , N-CoR2 , SMAP270 , SMRT , SMRTE , SMRTE-tau , TNRC14 , TRAC , TRAC-1 , TRAC1

Cellular Localization

Nucleus

Background

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]

Database

Research Area

DATA IMAGES

Anti-SMRT antibody used in IHC (Paraffin sections) (IHC-P). GTX66517

GTX66517 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX66517 SMRT antibody.
Dilution : 1:100

Anti-SMRT antibody used in IHC (Paraffin sections) (IHC-P). GTX66517

GTX66517 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX66517 SMRT antibody.
Dilution : 1:100

Anti-SMRT antibody used in Western Blot (WB). GTX66517

GTX66517 WB Image

WB analysis of various sample lysates using GTX66517 SMRT antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-SMRT antibody used in IHC (Paraffin sections) (IHC-P). GTX66517

GTX66517 IHC-P Image

IHC-P analysis of human colon tissue using GTX66517 SMRT antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399