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SMRT antibody

Cat No. GTX70245

Host

Mouse

Clonality

Polyclonal

Isotype

IgG

Application

WB, IP

Reactivity

Human
Package
50 μl ($259)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

275 kDa. ( Note )

Positive Control

HBL100

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4, containing no preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide from the human SMRT protein corresponding to amino acids 80-92 (QELHLRPESHSYL).

Purification

Protein G Affinity Purified
Antiserum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Nuclear Receptor Corepressor 2 , Ctg26 , N-Cor2 , Smap270 , Smrt , Smrte , Smrte-Tau , Tnrc14 , Trac , Trac-1 , Trac1 , Ncor2

Background

GTX70245 recognizes the Silencing Mediator for Retinoid and Thyroid receptors (SMRT) gene product, a 168 kDa nuclear protein. Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.

Database

Research Area

REFERENCE

There are currently no references for SMRT antibody (GTX70245). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 259