*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88021-PEP).
This antibody is expected to recognize both reported isoforms (NP_003816.2; NP_570710.1).
Mouse, Rat, Bovine(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide with sequence C-QIKRITDKAD, from the internal region of the protein sequence according to NP_003816.2; NP_570710.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Synaptosome Associated Protein 23,Hst17016,Snap-23,Snap23A,Snap23B,Snap23
Mainly localized to the plasma membrane.
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion
GTX88021 WB Image
WB analysis of human placenta lysate using GTX88021 SNAP23 antibody, Internal.
Dilution : 0.1µg/ml
Loading : 35µg protein in RIPA buffer
GTX88021 IHC-P Image
IHC-P analysis of human spleen using GTX88021 SNAP23 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml