GeneTex

  • Country / Location Selection

United States (US)

SNRPN antibody

Anti-SNRPN antibody used in Western Blot (WB). GTX114927
Anti-SNRPN antibody used in Western Blot (WB). GTX114927
Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX114927
Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX114927

Cat. No. GTX114927

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all SNRPN products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

Positive Control

Mouse heart , Jurkat

Predict Reactivity

Bovine, Chicken, Pig, Chimpanzee, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human SNRPN. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10620256

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

small nuclear ribonucleoprotein polypeptide N , HCERN3 , PWCR , RT-LI , SM-D , SMN , SNRNP-N , SNURF-SNRPN , sm-N

Cellular Localization

Nucleus

Background

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq]

Database

DATA IMAGES

Anti-SNRPN antibody used in Western Blot (WB). GTX114927

GTX114927 WB Image

Sample (50 ug of whole cell lysate)
A: mouse heart
12% SDS PAGE
GTX114927 diluted at 1:500

Anti-SNRPN antibody used in Western Blot (WB). GTX114927

GTX114927 WB Image

Sample (30 ug of whole cell lysate)
A: JurKat
12% SDS PAGE
GTX114927 diluted at 1:1000

Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX114927

GTX114927 IHC-P Image

SNRPN antibody detects SNRPN protein at cytosol on rat fore brain by immunohistochemical analysis.
Sample: Paraffin-embedded rat fore brain.
SNRPN antibody (GTX114927) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX114927

GTX114927 IHC-P Image

SNRPN antibody detects SNRPN protein at cytosol on mouse kidney by immunohistochemical analysis.
Sample: Paraffin-embedded mouse kidney.
SNRPN antibody (GTX114927) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

There are currently no references for SNRPN antibody (GTX114927). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for SNRPN antibody (GTX114927). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169