GeneTex
United States (US)

SNRPN antibody

Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX31617
Anti-SNRPN antibody used in Western Blot (WB). GTX31617
Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX31617

Cat No. GTX31617

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

Positive Control

THP-1 Cell Lysate(GTX27913) , Human Spleen Tissue Slide
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SNRPN antibody was raised against a 20 amino acid peptide near the amino terminus of human SNRPN.The immunogen is located within amino acids 30 - 80 of SNRPN.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Small Nuclear Ribonucleoprotein Polypeptide N,Hcern3,Pwcr,Rt-Li,Sm-D,Smn,Snrnp-N,Snurf-Snrpn,Sm-N,Snrpn

Background

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or

Database

DATA IMAGES
Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX31617

GTX31617 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31617 SNRPN antibody.
Working concentration : 20 μg/ml

Anti-SNRPN antibody used in Western Blot (WB). GTX31617

GTX31617 WB Image

WB analysis of THP-1 cell lysate using GTX31617 SNRPN antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-SNRPN antibody used in IHC (Paraffin sections) (IHC-P). GTX31617

GTX31617 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31617 SNRPN antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329