APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.5 - 1 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
THP-1 Cell Lysate(GTX27913) , Human Spleen Tissue Slide
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
SNRPN antibody was raised against a 20 amino acid peptide near the amino terminus of human SNRPN.The immunogen is located within amino acids 30 - 80 of SNRPN.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
small nuclear ribonucleoprotein polypeptide N , HCERN3 , PWCR , RT-LI , SM-D , SMN , SNRNP-N , SNURF-SNRPN , sm-N
Cellular Localization
Nucleus
Background
The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or
Database
DATA IMAGES
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GTX31617 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31617 SNRPN antibody.
Working concentration : 20 μg/ml
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GTX31617 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31617 SNRPN antibody.
Working concentration : 5 μg/ml
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GTX31617 WB Image
WB analysis of THP-1 cell lysate using GTX31617 SNRPN antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml
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REFERENCE
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REVIEW
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