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SOCS2 antibody [GT1326]

Recombinant antibody
Anti-SOCS2 antibody [GT1326] used in Western Blot (WB). GTX03238
Anti-SOCS2 antibody [GT1326] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX03238
Anti-SOCS2 antibody [GT1326] used in Western Blot (WB). GTX03238
Anti-SOCS2 antibody [GT1326] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX03238
Anti-SOCS2 antibody [GT1326] used in IHC (Paraffin sections) (IHC-P). GTX03238

Cat. No. GTX03238

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1326

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($439)
See all SOCS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human SOCS2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

suppressor of cytokine signaling 2 , CIS2 , Cish2 , SOCS-2 , SSI-2 , SSI2 , STATI2

Background

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Database

Research Area

DATA IMAGES

Anti-SOCS2 antibody [GT1326] used in Western Blot (WB). GTX03238

GTX03238 WB Image

Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with SOCS2 antibody [GT1326] (GTX03238) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-SOCS2 antibody [GT1326] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX03238

GTX03238 ICC/IF Image

ICC/IF analysis of NIH-3T3 cells using GTX03238 SOCS2 antibody [GT1326].
Blue : DAPI for nuclear staining
Dilution : 1:100

Anti-SOCS2 antibody [GT1326] used in Western Blot (WB). GTX03238

GTX03238 WB Image

WB analysis of various samples using GTX03238 SOCS2 antibody [GT1326].
Dilution : 1:1000
Loading : 25μg per lane

Anti-SOCS2 antibody [GT1326] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX03238

GTX03238 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX03238 SOCS2 antibody [GT1326].
Blue : DAPI for nuclear staining
Dilution : 1:100

Anti-SOCS2 antibody [GT1326] used in IHC (Paraffin sections) (IHC-P). GTX03238

GTX03238 IHC-P Image

IHC-P analysis of rat lung tissue section using GTX03238 SOCS2 antibody [GT1326].
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 439