GeneTex
United States (US)

SOD1 antibody

Cat No. GTX28866

Host Sheep
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

16 kDa. ( Note )

Specificity/Sensitivity

Shown to be specific by Western blotting and by gel diffusion techniques. Superoxide dismutases (SOD) arefound in all aerobic organisms, their physiological function appears to be to protect cells from free radicalsby scavenging superoxide anions. They catalyze the dismutation of superoxide anions to oxygen andhydrogen peroxide. SOD (Cu/Zn) is a cytosolic enzyme. SOD (Cu/Zn) is a dimer of two identical subunitsMW 16,000.
PROPERTIES

Form

Liquid

Buffer

Glycine Buffered Saline pH 7.4, 0.099% sodium azide, 0.1% EACA, 0.01% Benzamidine, 1 mM EDTA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

33.50mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human SOD Cu/Zn purified from human erythrocytes.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ALS1 Antibody , HSOD1 Antibody , SOD Antibody , IPOA Antibody , HOMODIMER Antibody , ALS Antibody

Cellular Localization

SOD (Cu/Zn) is a cytosolic enzyme.

Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

Package List Price ($)
$ 439